Chemistry

Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, bio... (Read more)

While the war on drugs is limited to a simplistic rallying cry of “no to drugs”, a diversity of approaches can open up new perspectives on the drug policies which have been tested since the beginning of the 20th Century. Living with Drugs presents the ... (Read more)

Biphasic Chemistry and The Solvent Case examines recent improvements in reaction conditions, in order to affirm the role of chemistry in the sustainable field. This book shows that those who work within the chemistry industry support limits for the use ... (Read more)

While very useful for studying syntheses of molecular diversity, multi-component reactions also offer rapid access to a variety of complex molecules that are relevant for biological applications. Multi-component Reactions in Molecular Diversity analyzes... (Read more)

Activation Methods examines recent improvements in the utilization of ultrasonic waves and pressurized gases to generate reactions. A straightforward method to use, sonochemistry allows chemical reactions to be carried out under ultrasound without the nee... (Read more)

For chemists, attempting to mimic nature by synthesizing complex natural products from raw material is a challenge that is fraught with pitfalls. To tackle this unique but potentially rewarding task, researchers can rely on well-established reactions and m... (Read more)

The projection of physical and chemical properties of basic compounds that are to be tested in drug design is fundamental, even before the launch of the synthesis program that leads to the development of a hit, as well as drugs that treat the pathology in ... (Read more)

This work presents crystalline solids in an original way, based firstly on their classification through the characteristics of atoms and ions (electronegativity, ionization potential, etc.). The bases of the crystallography are then proposed from observ... (Read more)

This book promotes the interaction between research and professional practices in the field of prevention and harm reduction. Through the scientific work and experience of human and social sciences researchers and medical social actors, research and action... (Read more)

Considering the challenge of sustainability facing our society in the coming decades, catalysis is without any doubt a research area of major importance. In this regard, asymmetric organocatalysis, now considered a pillar of green chemistry, deserves parti... (Read more)

Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role. These medicines result from molecules discovered by French researchers of the Institut de Chimie des Subst... (Read more)

Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; ... (Read more)