Edited by
Béatrice Clouet-d’Orval, CNRS and Center for Integrative Biology, Toulouse, France.
Bruno Franzetti, CNRS, France.
Philippe Oger, CNRS, France.
ISBN : 9781789451696
Publication Date : May 2025
Hardcover 252 pp
165.00 USD
Co-publisher
Archaea constitute a new branch of life alongside bacteria and eukaryotes. These microorganisms are unique in their cellular and molecular aspects. They have evolutionary links with the first eukaryotic cells and are now being used to elucidate fundamental biological questions.
Champions of extremophilicity, archaea are helping to lift the veil on the limits of life on Earth. Biology of Archaea 2 presents the diverse molecular mechanisms involved in the fundamental processes of genome maintenance and regulation of gene expression in archaeal cells.
This book analyzes the complex machinery involved in chromosome replication, DNA repair, RNA synthesis (transcription) and protein synthesis (translation), and explores the different classes of RNAs and enzymes involved in RNA maturation and degradation. These regulate the stability of messenger and regulatory non-coding RNAs, and contribute to the formation of the mature forms of ribosomal RNAs and transfer RNAs. These molecular mechanisms are closely related to those of eukaryotes.
1. Replication of Archaeal Chromosomes, Ghislaine Henneke, Roxane Lestini, Marc Nadal and Didier Flament.
2. Archaeal DNA Repair, Caroline L’Hermitte-Stead, Anaïs Bayard, Alexey Aleksandrov, Roxane Lestini and Hannu Myllykallio.
3. Transcription in Archaea, Thomas Fouqueau, Duy Khanh Phung and Ludovic Sauguet.
4. RNA Classes and Their Maturation and Degradation Enzymes, Manon Batista, Béatrice Clouet-D’Orval and Marie Bouvier.
5. Ribosome and Transfer RNA Biogenesis, Tamara Basta and Sébastien Ferreira-Cerca.
6. The Diversity and Function of Noncoding RNAs in Archaea, Hubert F. Becker and Christine Gaspin.
7. Translation in Archaea, Emmanuelle Schmitt and Yves Mechulam.
Béatrice Clouet-d’Orval is Research Director at the CNRS and works at the Center for Integrative Biology, Toulouse, France. Her main research areas focus on the post-transcriptional regulation of gene expression.
Bruno Franzetti is Research Director at the CNRS, France, where he specializes in the structural biology of archaea. His research areas include biophysical and cellular mechanisms that maintain proteome integrity under extreme conditions.
Philippe Oger is Research Director at the CNRS, France. His research areas include understanding the adaptations of prokaryotes in response to extreme conditions, using a multidisciplinary approach combining the methods derived from atomic physics and cutting-edge molecular biology and modeling.
