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Materials and Thermodynamics

Living and Economic Systems

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Mechanics of Aeronautical Composite Materials

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Finite Physical Dimensions Optimal Thermodynamics 1


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Co-design in Living Labs for Healthcare and Independent Living

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Metaheuristics Set Volume 10

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RCS Synthesis for Chipless RFID

Theory and Design

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Electronic Components and Elementary Functions

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Swift Ion Beam Analysis in Nanosciences

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Inside Anthropotechnology

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Ethics in Social Networking and Business 1

Theory, Practice and Current Recommendations

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Statistics for Bioinformatics

Methods for Multiple Sequence Alignement

Julie Dawn Thompson, University of Strasbourg, France

ISBN: 9781785482168

Publication Date: December 2016   Hardback   146 pp.

80.00 USD

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Next Generation Sequencing (NGS) has transformed the field of Biology. In the last ten years, the development of new genome sequencing technologies has made DNA sequencing, RNA-seq and high-throughput screening crucial research tools in areas like agriculture, medicine and the food industry.
The greatest challenge now lies in finding efficient and effective ways to manage the large-scale data being produced, to analyze the genome sequences and extract relevant and useful information.
In this book, the author introduces the fundamental concepts and traditional methods for comparative sequence analysis, as well as the most up-to-date multiple sequence alignment approaches currently being developed to cope with the volume and complexity of high-throughput genome sequencing data.


Part 1. Fundamental Concepts
1. Introduction.
Part 2. Traditional Multiple Sequence Alignment Methods
2. Heuristic Sequence Alignment Methods.
3. Statistical Alignment Approaches.
4. Multiple Alignment Quality Control.
5. Benchmarking.
Part 3. Large-scale Multiple Sequence Alignment Methods
6. Whole Genome Alignment.
7. Multiple Alignment of Thousands of Sequences.
8. Future Perspectives: High-Performance Computing.

About the Authors

Julie Dawn Thompson is a CNRS Research Director at the ICube Institute at the University of Strasbourg, France.


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