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Secure Connected Objects

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Banach, Fréchet, Hilbert and Neumann Spaces

Analysis for PDEs Set Volume 1

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Semi-Markov Migration Models for Credit Risk

Stochastic Models for Insurance Set Volume 1

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Human Exposure to Electromagnetic Fields

From Extremely Low Frequency (ELF) to Radio Frequency

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Enterprise Interoperability


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Data Treatment in Environmental Sciences

Multivaried Approach

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From Pinch Methodology to Pinch-Exergy Integration of Flexible Systems

Thermodynamics Energy, Environment, Economy Set

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Exterior Algebras

Elementary Tribute to Grassmann's Ideas

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Nonlinear Theory of Elastic Plates

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Cognitive Approach to Natural Language Processing

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Statistics for Bioinformatics

Statistics for Bioinformatics Set

Julie Dawn Thompson, University of Strasbourg, France

ISBN: 9781785482168

Publication Date: December 2016   Hardback   146 pp.

80.00 USD

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Next Generation Sequencing (NGS) has transformed the field of Biology. In the last ten years, the development of new genome sequencing technologies has made DNA sequencing, RNA-seq and high-throughput screening crucial research tools in areas like agriculture, medicine and the food industry.
The greatest challenge now lies in finding efficient and effective ways to manage the large-scale data being produced, to analyze the genome sequences and extract relevant and useful information.
In this book, the author introduces the fundamental concepts and traditional methods for comparative sequence analysis, as well as the most up-to-date multiple sequence alignment approaches currently being developed to cope with the volume and complexity of high-throughput genome sequencing data.


Part 1. Fundamental Concepts
1. Introduction.
Part 2. Traditional Multiple Sequence Alignment Methods
2. Heuristic Sequence Alignment Methods.
3. Statistical Alignment Approaches.
4. Multiple Alignment Quality Control.
5. Benchmarking.
Part 3. Large-scale Multiple Sequence Alignment Methods
6. Whole Genome Alignment.
7. Multiple Alignment of Thousands of Sequences.
8. Future Perspectives: High-Performance Computing.

About the Authors

Julie Dawn Thompson is a CNRS Research Director at the ICube Institute at the University of Strasbourg, France.


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