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Forthcoming

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Reliability Investigation of LED Devices for Public Light Applications

Durability, Robustness and Reliability of Photonic Devices Set

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Aerospace Actuators 2

Signal-by-Wire and Power-by-Wire

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Flash Memory Integration

Performance and Energy Considerations

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Mechanics of Aeronautical Solids, Materials and Structures

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Engineering Investment Process

Making Value Creation Repeatable

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Space Strategy

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Distributed Systems

Concurrency and Consistency

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Fatigue of Textile and Short Fiber Reinforced Composites

Durability and Ageing of Organic Composite Materials Set Volume 1

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Management of the Effects of Coastal Storms

Policy, Scientific and Historical Perspectives

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Computational Color Science

Variational Retinex-like Methods

Browse Titles by Subject

Molecular, Green, Medical and Pharma. Chemistry

Navelbine® and Taxotere®

Histories of Sciences

Muriel Le Roux, CNRS, France Françoise Guéritte, ICSN/CNRS, France

Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.
These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the...

December 2016
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Dynemicin A, Uncialamycin and Analogues

Isolation, Biological Activities and Syntheses

Daniel Best, University of Rennes 1, France Mickael Jean, University of Rennes 1, France Pierre van de Weghe, University of Rennes 1, France

Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.
Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which ...

July 2016
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