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Forthcoming

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Wall Turbulence Control

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From Photon to Pixel – Revised and Updated 2nd Edition

The Digital Camera Handbook

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Fluid–Structure Interactions and Uncertainties

Ansys and Fluent Tools

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Stochastic Analysis of Risk and Management

Stochastic Models in Survival Analysis and Reliability Set – Volume 2

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Musical Techniques

Frequencies and Harmony

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Location Strategies and Value Creation of International Mergers and Acquisitions

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Current and Emerging Issues in the Audiovisual Industry

Diverse and Global Perspectives on Value Creation Set – Volume 1

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International Specialization Dynamics

Smart Innovation Set – Volume 9

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Reflexive Governance for Research and Innovative Knowledge

Responsible Research and Innovation Set – Volume 6

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Reliability Investigation of LED Devices for Public Light Applications

Durability, Robustness and Reliability of Photonic Devices Set

Browse Titles by Subject

Molecular, Green, Medical and Pharma. Chemistry

Navelbine® and Taxotere®

Histories of Sciences

Muriel Le Roux, CNRS, France Françoise Guéritte, ICSN/CNRS, France

Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.
These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the...

December 2016
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Dynemicin A, Uncialamycin and Analogues

Isolation, Biological Activities and Syntheses

Daniel Best, University of Rennes 1, France Mickael Jean, University of Rennes 1, France Pierre van de Weghe, University of Rennes 1, France

Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.
Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which ...

July 2016
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