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Forthcoming

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Secure Connected Objects

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Banach, Fréchet, Hilbert and Neumann Spaces

Analysis for PDEs Set Volume 1

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Semi-Markov Migration Models for Credit Risk

Stochastic Models for Insurance Set Volume 1

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Human Exposure to Electromagnetic Fields

From Extremely Low Frequency (ELF) to Radio Frequency

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Enterprise Interoperability

INTEROP-PGSO Vision

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Data Treatment in Environmental Sciences

Multivaried Approach

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From Pinch Methodology to Pinch-Exergy Integration of Flexible Systems

Thermodynamics Energy, Environment, Economy Set

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Exterior Algebras

Elementary Tribute to Grassmann's Ideas

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Nonlinear Theory of Elastic Plates

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Cognitive Approach to Natural Language Processing

Browse Titles by Subject

Molecular, Green, Medical and Pharma. Chemistry

Navelbine® and Taxotere®

Histories of Sciences

Muriel Le Roux, CNRS, France Françoise Guéritte, ICSN/CNRS, France

Among the many forms of cancer treatment, chemotherapy remains an important part of the arsenal in which Navelbine and Taxotere play a major role.
These medicines result from molecules discovered by French researchers of the Institut de Chimie des Substances Naturelles (ICSN) of the CNRS, directed by Pierre Potier. By recounting this history, the authors of this book attempt to illustrate how the...

December 2016
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Dynemicin A, Uncialamycin and Analogues

Isolation, Biological Activities and Syntheses

Daniel Best, University of Rennes 1, France Mickael Jean, University of Rennes 1, France Pierre van de Weghe, University of Rennes 1, France

Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis.
Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which ...

July 2016
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